Pesquisa sobre: SQUALENE MONOOXYGENASE 
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Descritor Inglês:   Squalene Monooxygenase 
Descritor Espanhol:   Escualeno-Monooxigenasa 
Descritor Português:   Esqualeno Mono-Oxigenase 
Sinônimos Inglês:   Epoxidase, Squalene
Monooxygenase, Squalene
Squalene Epoxidase
Squalene Monooxygenase (2,3-Epoxidizing)  
Categoria:   D08.811.682.690.708.749
Definição Inglês:   The second enzyme in the committed pathway for CHOLESTEROL biosynthesis, this enzyme catalyzes the first oxygenation step in the biosynthesis of STEROLS and is thought to be a rate limiting enzyme in this pathway. Specifically, this enzyme catalyzes the conversion of SQUALENE to (S)-squalene-2,3-epoxide. 
Nota Histórica Inglês:   2006(1980); use ETHERS, CYCLIC 1970-1979 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número do Registro:   50664 
Identificador Único:   D050603 

Ocorrência na BVS:
 

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